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Descriptor English: Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
Descriptor Spanish: Subunidad Apc1 del Ciclosoma-Complejo Promotor de la Anafase
Descriptor subunidad Apc1 del complejo promotor de la anafase-ciclosoma
Entry term(s) Anapc1
subunidad Apc1 del ciclosoma
subunidad Apc1 del ciclosoma o complejo promotor de la anafase
subunidad Apc1 del complejo promotor de la anafase
subunidad Apc1 del complejo promotor de la anafase o ciclosoma
Scope note: La subunidad de mayor tamaño del complejo promotor de la anafase. Actúa principalmente como andamio para la organización y disposición de las subunidades. La región C-terminal de Apc-1 contiene una serie de repeticiones de aminoácidos en tándem que también existen en la partícula 26S reguladora del proteasoma y coopera en la formación y estabilización de las interrelaciones entre proteínas.
Descriptor Portuguese: Subunidade Apc1 do Ciclossomo-Complexo Promotor de Anáfase
Descriptor French: Sous-unité APC1 du complexe promoteur de l'anaphase
Entry term(s): Anapc1
Apc1 Subunit, Anaphase Promoting Complex
Apc1 Subunit, Anaphase Promoting Complex Cyclosome
Apc1 Subunit, Anaphase-Promoting Complex
Tree number(s): D08.811.464.938.750.092.500
D12.776.167.024.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064189
Scope note: The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Cycle Proteins (1996-2003)
Ligases (1996-2003)
Ubiquitin-Protein Ligase Complexes (2004-2013)
Public MeSH Note: 2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013
History Note: 2014
DeCS ID: 55273
Unique ID: D064189
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - Preferred
Concept UI M0580156
Scope note The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions.
Preferred term Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
Entry term(s) Anapc1
Apc1 Subunit, Anaphase Promoting Complex
Apc1 Subunit, Anaphase Promoting Complex Cyclosome
Apc1 Subunit, Anaphase-Promoting Complex



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