Descriptor English: | Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome | ||||||
Descriptor Spanish: |
Subunidad Apc2 del Ciclosoma-Complejo Promotor de la Anafase
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Descriptor Portuguese: | Subunidade Apc2 do Ciclossomo-Complexo Promotor de Anáfase | ||||||
Descriptor French: | Sous-unité APC2 du complexe promoteur de l'anaphase | ||||||
Entry term(s): |
Anapc2 Apc2 Subunit, Anaphase Promoting Complex Apc2 Subunit, Anaphase Promoting Complex Cyclosome Apc2 Subunit, Anaphase-Promoting Complex |
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Tree number(s): |
D08.811.464.938.750.092.750 D12.776.167.024.750 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064190 | ||||||
Scope note: | Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.3.2.27 | ||||||
Previous Indexing: |
Cell Cycle Proteins (1996-2003) Ligases (1996-2003) Ubiquitin-Protein Ligase Complexes (2003-2013) |
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Public MeSH Note: | 2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013 |
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History Note: | 2014 |
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DeCS ID: | 55276 | ||||||
Unique ID: | D064190 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2014/01/01 | ||||||
Date of Entry: | 2013/07/08 | ||||||
Revision Date: | 2016/06/02 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome
- Preferred
Concept UI |
M0580157 |
Scope note | Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions. |
Preferred term | Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome |
Entry term(s) |
Anapc2 Apc2 Subunit, Anaphase Promoting Complex Apc2 Subunit, Anaphase Promoting Complex Cyclosome Apc2 Subunit, Anaphase-Promoting Complex |
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