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Descriptor English: Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome
Descriptor Spanish: Subunidad Apc10 del Ciclosoma-Complejo Promotor de la Anafase
Descriptor subunidad Apc10 del complejo promotor de la anafase-ciclosoma
Entry term(s) Anapc10
subunidad Apc10 del ciclosoma
subunidad Apc10 del ciclosoma o complejo promotor de la anafase
subunidad Apc10 del complejo promotor de la anafase
subunidad Apc10 del complejo promotor de la anafase o ciclosoma
Scope note: Apc10 es necesaria para el reconocimiento del sustrato dependiente del coactivador por el complejo promotor de la anafase/ciclosoma. Se une a la subunidad Apc2, que es parte del núcleo catalítico, e interactúa con coactivadores Cdh1 o Cdc20 para reclutar sustratos al complejo.
Descriptor Portuguese: Subunidade Apc10 do Ciclossomo-Complexo Promotor de Anáfase
Descriptor French: Sous-unité APC10 du complexe promoteur de l'anaphase
Entry term(s): Anapc10
Apc10 Subunit, Anaphase Promoting Complex
Apc10 Subunit, Anaphase-Promoting Complex
Tree number(s): D08.811.464.938.750.092.625
D12.776.167.024.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064197
Scope note: Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Cycle Proteins (1996-2013)
Ligases (1996-2003)
Ubiquitin-Protein Ligase Complexes (2004-2013)
Public MeSH Note: 2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013
History Note: 2014
DeCS ID: 55274
Unique ID: D064197
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome - Preferred
Concept UI M0580184
Scope note Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.
Preferred term Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome
Entry term(s) Anapc10
Apc10 Subunit, Anaphase Promoting Complex
Apc10 Subunit, Anaphase-Promoting Complex



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