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Descriptor English: Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome
Descriptor Spanish: Subunidad Apc11 del Ciclosoma-Complejo Promotor de la Anafase
Descriptor subunidad Apc11 del complejo promotor de la anafase-ciclosoma
Entry term(s) Anapc11
subunidad Apc11 del ciclosoma
subunidad Apc11 del ciclosoma o complejo promotor de la anafase
subunidad Apc11 del complejo promotor de la anafase
subunidad Apc11 del complejo promotor de la anafase o ciclosoma
Scope note: Junto a la subunidad Apc2, forma el núcleo catalítico de la ubicuitina ligasa E3, complejo promotor de la anafase-ciclosoma (APC-C). Tiene un dominio RING H2 que interactúa con el dominio culina de la Apc2. La Apc11 también interactúa con las ubiquitina ligasas E2 implicadas con las reacciones de ubiquitinación APC-C.
Descriptor Portuguese: Subunidade Apc11 do Ciclossomo-Complexo Promotor de Anáfase
Descriptor French: Sous-unité APC11 du complexe promoteur de l'anaphase
Entry term(s): Anapc11
Apc11 Subunit, Anaphase Promoting Complex
Apc11 Subunit, Anaphase Promoting Complex Cyclosome
Apc11 Subunit, Anaphase-Promoting Complex
Tree number(s): D08.811.464.938.750.092.687
D12.776.167.024.687
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064198
Scope note: Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.2.27
Previous Indexing: Cell Cycle Proteins (1996-2013)
Ligases (1996-2003)
Ubiquitin-Protein Ligase Complexes (2004-2013)
Public MeSH Note: 2014; was indexed under UBIQUITIN-PROTEIN LIGASE COMPLEXES 2004-2013
History Note: 2014
DeCS ID: 55275
Unique ID: D064198
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2016/06/02
Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome - Preferred
Concept UI M0580185
Scope note Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.
Preferred term Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome
Entry term(s) Anapc11
Apc11 Subunit, Anaphase Promoting Complex
Apc11 Subunit, Anaphase Promoting Complex Cyclosome
Apc11 Subunit, Anaphase-Promoting Complex



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