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Descriptor English: Sterile Alpha Motif
Descriptor Spanish: Motivo alfa Estéril
Descriptor motivo alfa estéril
Entry term(s) dominio SAM
dominio con motivo alfa estéril
Scope note: Módulo de posible interacción con proteínas, de aproximadamente 70 aminoácidos de longitud, que forma un pequeño ovillo de cinco hélices con dos grandes interfaces que pueden homo o heteroligomerizarse, o unirse a un motivo alfa no estéril. El motivo alfa estéril se encuentra en una gran variedad de proteínas eucariotas que actúan en distintos procesos biológicos.
Descriptor Portuguese: Motivo Estéril alfa
Descriptor French: Motif stérile alpha
Entry term(s): Motif, Sterile Alpha
Motifs, Sterile Alpha
SAM Domain
SAM Domains
Sterile Alpha Motif Domain
Sterile Alpha Motifs
Tree number(s): G02.111.570.820.709.275.500.898
G02.111.570.820.709.275.750.500.813
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071682
Scope note: A putative protein interaction module, approximately 70 amino acids long, that forms a small five-helix bundle with two large interfaces which may homo- and hetero-oligomerize, or bind non-sterile-alpha motif targets. The sterile alpha motif is present in a wide variety of eukaryotic proteins that function in diverse biological processes.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Protein Structure, Tertiary (1998-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56734
Unique ID: D000071682
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09
Sterile Alpha Motif - Preferred
Concept UI M000615312
Scope note A putative protein interaction module, approximately 70 amino acids long, that forms a small five-helix bundle with two large interfaces which may homo- and hetero-oligomerize, or bind non-sterile-alpha motif targets. The sterile alpha motif is present in a wide variety of eukaryotic proteins that function in diverse biological processes.
Preferred term Sterile Alpha Motif
Entry term(s) Motif, Sterile Alpha
Motifs, Sterile Alpha
SAM Domain
SAM Domains
Sterile Alpha Motif Domain
Sterile Alpha Motifs



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