| Descriptor English: | Short Stature Homeobox Protein | ||||||
| Descriptor Spanish: |
Proteína de la Caja Homeótica de Baja Estatura
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| Descriptor Portuguese: | Proteína de Homoeobox de Baixa Estatura | ||||||
| Descriptor French: | Protéine homéotique associée à la petite taille | ||||||
| Entry term(s): |
GCFX Protein PHOG Protein SHOX Protein SHOXY Protein |
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| Tree number(s): |
D12.776.260.400.859 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074122 | ||||||
| Scope note: | A homeodomain protein that is highly expressed in the nuclei of skeletal muscle, bone marrow, and osteogenic cells and has critical roles in growth and development. Its gene resides within PSEUDOAUTOSOMAL REGION 1 of X and Y chromosomes and mutations are associated with several growth disorders including LERI-WEIL SYNDROME; LANGER MESOMELIC DYSPLASIA; and SHORT STATURE, IDIOPATHIC, X-LINKED. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Homeodomain Proteins (1997-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57111 | ||||||
| Unique ID: | D000074122 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/02/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Short Stature Homeobox Protein
- Preferred
| Concept UI |
M000625710 |
| Scope note | A homeodomain protein that is highly expressed in the nuclei of skeletal muscle, bone marrow, and osteogenic cells and has critical roles in growth and development. Its gene resides within PSEUDOAUTOSOMAL REGION 1 of X and Y chromosomes and mutations are associated with several growth disorders including LERI-WEIL SYNDROME; LANGER MESOMELIC DYSPLASIA; and SHORT STATURE, IDIOPATHIC, X-LINKED. |
| Preferred term | Short Stature Homeobox Protein |
| Entry term(s) |
GCFX Protein PHOG Protein SHOX Protein SHOXY Protein |
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