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Descriptor English: Otx Transcription Factors
Descriptor Spanish: Factores de Transcripción Otx
Descriptor factores de transcripción Otx
Scope note: Familia de proteínas de homeodominio de los VERTEBRADOS, homólogas de las proteínas orthodenticle de Drosophila. Regulan la TRANSCRIPCIÓN GENÉTICA y tienen un destacado papel en el DESARROLLO EMBRIONARIO del CEREBRO.
Descriptor Portuguese: Fatores de Transcrição Otx
Descriptor French: Facteurs de transcription Otx
Entry term(s): Homeobox Protein OTX1
Homeobox Protein OTX2
Homeodomain Proteins, Otx
OTX1, Homeobox Protein
OTX2, Homeobox Protein
Orthodenticle Homolog Homeodomain Proteins
Otx Homeodomain Proteins
Otx1 Transcription Factor
Otx2 Transcription Factor
Transcription Factor, Otx1
Transcription Factor, Otx2
Transcription Factors, Otx
Tree number(s): D12.776.260.400.718
D12.776.930.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051857
Scope note: A family of VERTEBRATE homeodomain proteins that share homology with orthodenticle protein, Drosophila. They regulate GENETIC TRANSCRIPTION and play an important role in EMBRYONIC DEVELOPMENT of the BRAIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; OTX TRANSCRIPTION FACTORS was indexed under HOMEODOMAIN PROTEINS 2000-2005
History Note: 2006(2000)
DeCS ID: 51009
Unique ID: D051857
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/06/29
Otx Transcription Factors - Preferred
Concept UI M0364810
Scope note A family of VERTEBRATE homeodomain proteins that share homology with orthodenticle protein, Drosophila. They regulate GENETIC TRANSCRIPTION and play an important role in EMBRYONIC DEVELOPMENT of the BRAIN.
Preferred term Otx Transcription Factors
Entry term(s) Homeodomain Proteins, Otx
Orthodenticle Homolog Homeodomain Proteins
Otx Homeodomain Proteins
Transcription Factors, Otx
Otx2 Transcription Factor - Narrower
Concept UI M0219147
Preferred term Otx2 Transcription Factor
Entry term(s) Homeobox Protein OTX2
OTX2, Homeobox Protein
Transcription Factor, Otx2
Otx1 Transcription Factor - Narrower
Concept UI M0481976
Preferred term Otx1 Transcription Factor
Entry term(s) Homeobox Protein OTX1
OTX1, Homeobox Protein
Transcription Factor, Otx1



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