| Descriptor English: | Zinc Finger E-box-Binding Homeobox 1 | ||||||
| Descriptor Spanish: |
Homeobox 1 de Unión a la E-Box con Dedos de Zinc
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| Descriptor Portuguese: | Homeobox 1 de Ligação a E-box em Dedo de Zinco | ||||||
| Descriptor French: | Facteur de transcription Zeb1 | ||||||
| Entry term(s): |
NIL 2 A Zinc Finger Protein NIL-2-A Zinc Finger Protein TCF8 Protein Transcription Factor 8 Transcription Factor, Zeb1 Zeb1 Transcription Factor Zinc Finger E box Binding Homeobox 1 |
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| Tree number(s): |
D12.776.260.400.906 D12.776.260.703.800 D12.776.930.780.945 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071799 | ||||||
| Scope note: | A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Homeodomain Proteins (2004-2016) Transcription Factors (2004-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56604 | ||||||
| Unique ID: | D000071799 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/04/15 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Zinc Finger E-box-Binding Homeobox 1
- Preferred
| Concept UI |
M000615551 |
| Scope note | A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation. |
| Preferred term | Zinc Finger E-box-Binding Homeobox 1 |
| Entry term(s) |
NIL 2 A Zinc Finger Protein NIL-2-A Zinc Finger Protein TCF8 Protein Transcription Factor 8 Transcription Factor, Zeb1 Zeb1 Transcription Factor Zinc Finger E box Binding Homeobox 1 |
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