| Descriptor English: | Zinc Finger E-box Binding Homeobox 2 | ||||||
| Descriptor Spanish: |
Caja Homeótica 2 de Unión a E-Box con Dedos de Zinc
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| Descriptor Portuguese: | Homeobox 2 de Ligação a E-box com Dedos de Zinco | ||||||
| Descriptor French: | Facteur de transcription Zeb2 | ||||||
| Entry term(s): |
Smad Interacting Protein 1 Smad-Interacting Protein 1 Transcription Factor, Zeb2 Zeb2 Transcription Factor Zinc Finger E box Binding Homeobox 2 Zinc Finger E box Binding Homeobox 2 Protein Zinc Finger E-box Binding Homeobox 2 Protein |
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| Tree number(s): |
D12.776.260.400.883 D12.776.260.703.700 D12.776.930.780.918 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074165 | ||||||
| Scope note: | A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Homeodomain Proteins (2004-2017) Repressor Proteins (2004-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57113 | ||||||
| Unique ID: | D000074165 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/02/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Zinc Finger E-box Binding Homeobox 2
- Preferred
| Concept UI |
M000625738 |
| Scope note | A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME. |
| Preferred term | Zinc Finger E-box Binding Homeobox 2 |
| Entry term(s) |
Smad Interacting Protein 1 Smad-Interacting Protein 1 Transcription Factor, Zeb2 Zeb2 Transcription Factor Zinc Finger E box Binding Homeobox 2 Zinc Finger E box Binding Homeobox 2 Protein Zinc Finger E-box Binding Homeobox 2 Protein |
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