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Descriptor English: Myeloid Ecotropic Viral Integration Site 1 Protein
Descriptor Spanish: Proteína 1 del Sitio de Integración Viral Ecotrópica Mieloide
Descriptor proteína 1 del sitio de integración viral ecotrópica mieloide
Entry term(s) factor de transcripción Meis1
proteína MEIS1
proteína homeobox MEIS1
Scope note: Proteína con homeodominio tipo TALE y factor de transcripción que funciona como regulador de la expresión de la PROTEÍNA PAX6 y como activador de la expresión del gen del FACTOR PLAQUETARIO 4. Es esencial para la hematopoyesis, la diferenciación de los MEGACARIOCITOS y para la configuración vascular. También interviene en la inducción de leucemias mieloides.
Descriptor Portuguese: Proteína Meis1
Descriptor French: Protéine du site-1 d'intégration des virus myéloïdes écotropiques
Entry term(s): Homeobox Protein MEIS1
MEIS1, Homeobox Protein
Meis 1 Protein
Meis-1 Protein
Meis1 Protein
Meis1 Transcription Factor
Transcription Factor, Meis1
Tree number(s): D12.776.260.400.483
D12.776.930.462
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075064
Scope note: A TALE-type homeodomain protein and transcription factor that functions as a regulator of PAX6 PROTEIN expression and as an activator of PLATELET FACTOR 4 gene expression. It is essential for hematopoiesis, differentiation of MEGAKARYOCYTES, and vascular patterning. It may also have a role in the induction of myeloid leukemias.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2018; MYELOID ECOTROPIC VIRAL INTEGRATION SITE 1 PROTEIN was indexed under NEOPLASM PROTEINS and HOMEODOMAIN PROTEINS 1995-2017
History Note: 2018 (1995)
DeCS ID: 57109
Unique ID: D000075064
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22
Myeloid Ecotropic Viral Integration Site 1 Protein - Preferred
Concept UI M000629053
Scope note A TALE-type homeodomain protein and transcription factor that functions as a regulator of PAX6 PROTEIN expression and as an activator of PLATELET FACTOR 4 gene expression. It is essential for hematopoiesis, differentiation of MEGAKARYOCYTES, and vascular patterning. It may also have a role in the induction of myeloid leukemias.
Preferred term Myeloid Ecotropic Viral Integration Site 1 Protein
Entry term(s) Homeobox Protein MEIS1
MEIS1, Homeobox Protein
Meis 1 Protein
Meis-1 Protein
Meis1 Protein
Meis1 Transcription Factor
Transcription Factor, Meis1



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