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Descriptor English: Homeobox Protein Nkx-2.2
Descriptor Spanish: Proteína Homeobox Nkx-2.2
Descriptor proteína homeobox Nkx-2.2
Entry term(s) proteína Nkx-2.2
proteína Nkx2.2
proteína con homeodominio Nkx-2.2
proteína de homeodominio Nkx-2.2
Scope note: Factor de transcripción que contiene una homeosecuencia que funciona en las CÉLULAS SECRETORAS DE INSULINA. Las mutaciones en el gen NKX2-2 se asocian a DIABETES MELLITUS DEL ADULTO de inicio juvenil y a OLIGODENDROGLIOMA.
Descriptor Portuguese: Proteína Homeobox Nkx-2.2
Descriptor French: Homéoprotéine Nkx-2.2
Entry term(s): Nkx 2.2 Protein
Nkx-2.2 Homeodomain Protein
Nkx-2.2 Protein
Nkx2.2 Protein
Protein, Nkx2.2
Tree number(s): D12.776.260.400.230
D12.776.660.415
D12.776.930.321
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000090322
Scope note: A homeobox-containing transcription factor that functions in INSULIN-SECRETING CELLS. Mutations in the NKX2-2 gene are associated with MATURITY-ONSET DIABETES OF THE YOUNG and OLIGODENDROGLIOMA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2022; NKX2.2 PROTEIN was indexed under HOMEODOMAIL PROTEINS and ZEBRAFISH PROTEINS 1997-2021
History Note: 2022 (1995)
DeCS ID: 59792
Unique ID: D000090322
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/11/19
Homeobox Protein Nkx-2.2 - Preferred
Concept UI M000746069
Scope note A homeobox-containing transcription factor that functions in INSULIN-SECRETING CELLS. Mutations in the NKX2-2 gene are associated with MATURITY-ONSET DIABETES OF THE YOUNG and OLIGODENDROGLIOMA.
Preferred term Homeobox Protein Nkx-2.2
Entry term(s) Nkx 2.2 Protein
Nkx-2.2 Homeodomain Protein
Nkx-2.2 Protein
Nkx2.2 Protein
Protein, Nkx2.2



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