Descriptor English: | Thyroid Nuclear Factor 1 | ||||||
Descriptor Spanish: |
Factor Nuclear Tiroideo 1
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Descriptor Portuguese: | Fator Nuclear 1 de Tireoide | ||||||
Descriptor French: | Facteur-1 de transcription de la thyroïde | ||||||
Entry term(s): |
Enhancer-Binding Protein, Thyroid-Specific Homeobox Protein Nkx 2.1 Homeobox Protein Nkx-2.1 NK2 Homeobox 1 Protein Nkx-2.1, Homeobox Protein TITF 1 Protein TITF-1 Protein TITF1 Protein TTF 1 Thyroid Nuclear Factor TTF-1 Thyroid Nuclear Factor Thyroid Specific Enhancer Binding Protein Thyroid Transcription Factor 1 Thyroid-Specific Enhancer-Binding Protein |
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Tree number(s): |
D12.776.260.400.871 D12.776.660.823 D12.776.930.888 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074482 | ||||||
Scope note: | A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Public MeSH Note: | 2018; THYROID NUCLEAR FACTOR 1 was indexed under NUCLEAR PROTEINS and TRANSCRIPTION FACTORS 1990-2017 |
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History Note: | 2018 (1990) |
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DeCS ID: | 57112 | ||||||
Unique ID: | D000074482 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2018/01/01 | ||||||
Date of Entry: | 2017/07/11 | ||||||
Revision Date: | 2017/04/06 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Thyroid Nuclear Factor 1
- Preferred
Concept UI |
M0181663 |
Scope note | A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY. |
Preferred term | Thyroid Nuclear Factor 1 |
Entry term(s) |
Enhancer-Binding Protein, Thyroid-Specific Homeobox Protein Nkx 2.1 Homeobox Protein Nkx-2.1 NK2 Homeobox 1 Protein Nkx-2.1, Homeobox Protein TITF 1 Protein TITF-1 Protein TITF1 Protein TTF 1 Thyroid Nuclear Factor TTF-1 Thyroid Nuclear Factor Thyroid Specific Enhancer Binding Protein Thyroid Transcription Factor 1 Thyroid-Specific Enhancer-Binding Protein |
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