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Descriptor English: Loperamide
Descriptor Spanish: Loperamida
Descriptor loperamida
Scope note: ANTIDIARREICO sintético de acción prolongada, que tiene escasa absorción a nivel intestinal y carece de efectos sobre el sistema adrenergico o el sistema nervioso central, aunque puede actuar como antagonista de la histamina e interferir con la acetilcolina liberada localmente.
Descriptor Portuguese: Loperamida
Descriptor French: Lopéramide
Entry term(s): Chlorhydrate de lopéramide
R-18553
R18553
Tree number(s): D03.383.621.440
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008139
Scope note: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antidiarrheals
Registry Number: 6X9OC3H4II
CAS Type 1 Name: 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-
DeCS ID: 8314
Unique ID: D008139
NLM Classification: QV 71
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2016/05/31
Lopéramide - Preferred
Concept UI M0012692
Preferred term Lopéramide
R-18553 - Narrower
Concept UI M0012693
Preferred term R-18553
Entry term(s) R18553
Chlorhydrate de lopéramide - Narrower
Concept UI M0330089
Preferred term Chlorhydrate de lopéramide



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