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Descriptor English: Mafenide
Descriptor Spanish: Mafenida
Descriptor Portuguese: Mafenida
Descriptor French: Mafénide
Entry term(s): 4 Homosulfanilamide
4-Homosulfanilamide
Bensulfamide
Mafenide Acetate
Mafylon
Maphenid
Marfanil
Napaltan
Sulfabenzamine
Sulfamylon
Tree number(s): D02.065.884.570
D02.886.590.700.570
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008272
Scope note: A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Infective Agents, Local
Anti-Bacterial Agents
Carbonic Anhydrase Inhibitors
Registry Number: 58447S8P4L
CAS Type 1 Name: Benzenesulfonamide, 4-(aminomethyl)-
Previous Indexing: Sulfonamides (1970-1974)
Tosyl Compounds (1973-1974)
Public MeSH Note: 1991; was see under SULFONAMIDES 1975-1990
History Note: 1991 (1975); was see under SULFONAMIDES 1975-1990
DeCS ID: 8446
Unique ID: D008272
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2018/05/21
Mafenide - Preferred
Concept UI M0012880
Scope note A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.
Preferred term Mafenide
Entry term(s) Maphenid
Mafenide Acetate - Narrower
Concept UI M0012881
Preferred term Mafenide Acetate
Sulfamylon - Narrower
Concept UI M0350903
Preferred term Sulfamylon
Marfanil - Narrower
Concept UI M0350904
Preferred term Marfanil
Napaltan - Narrower
Concept UI M0012882
Preferred term Napaltan
4-Homosulfanilamide - Narrower
Concept UI M000642438
Preferred term 4-Homosulfanilamide
Entry term(s) 4 Homosulfanilamide
Bensulfamide
Sulfabenzamine
Mafylon - Narrower
Concept UI M0350905
Preferred term Mafylon



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