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Descriptor English: Phencyclidine
Descriptor Spanish: Fenciclidina
Descriptor fenciclidina
Scope note: Alucinógeno utilizado antiguamente como anestésico veterinario y brevemente como anestésico general en humanos. La fenciclidina es similar a la KETAMINA en cuanto a estructura y mucho de sus efectos. Como la ketamina, puede producir un estado disociativo. Ejerce su acción farmacológica a través de la inhibición de los receptores NMDA (RECEPTORES DE N-METIL-D-ASPARTATO). Como droga de abuso es conocida como PCP y Polvo de Angel.
Descriptor Portuguese: Fenciclidina
Descriptor French: Phencyclidine
Entry term(s): 1-(1-Phenylcyclohexyl)piperidine
Angel Dust
CL 395
CL-395
CL395
Dust, Angel
GP 121
GP-121
GP121
Phencyclidine Hydrobromide
Phencyclidine Hydrochloride
Sernyl
Serylan
Tree number(s): D03.383.621.699
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010622
Scope note: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Enzyme Inhibitors
Hallucinogens
Excitatory Amino Acid Antagonists
Registry Number: J1DOI7UV76
CAS Type 1 Name: Piperidine, 1-(1-phenylcyclohexyl)-
Previous Indexing: Anesthetics (1966-1972)
Piperidines (1968-1972)
Public MeSH Note: 73; was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967.
History Note: 73(64); was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967
Related: Phencyclidine Abuse MeSH
Receptors, Phencyclidine MeSH
DeCS ID: 10812
Unique ID: D010622
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Phencyclidine - Preferred
Concept UI M0016495
Scope note A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Preferred term Phencyclidine
Entry term(s) 1-(1-Phenylcyclohexyl)piperidine
Angel Dust
Dust, Angel
GP-121 - Narrower
Concept UI M0016496
Preferred term GP-121
Entry term(s) GP 121
GP121
Serylan - Narrower
Concept UI M0016498
Preferred term Serylan
Phencyclidine Hydrochloride - Narrower
Concept UI M0329830
Preferred term Phencyclidine Hydrochloride
Sernyl - Narrower
Concept UI M0016497
Preferred term Sernyl
CL-395 - Narrower
Concept UI M0373872
Preferred term CL-395
Entry term(s) CL 395
CL395
Phencyclidine Hydrobromide - Narrower
Concept UI M0329829
Preferred term Phencyclidine Hydrobromide



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