| Descriptor English: | Phencyclidine |
| Descriptor Spanish: | Fenciclidina |
| Descriptor Portuguese: | Fenciclidina |
| Descriptor French: | Phencyclidine |
| Entry term(s): |
1-(1-Phenylcyclohexyl)piperidine Angel Dust CL 395 CL-395 CL395 Dust, Angel GP 121 GP-121 GP121 Phencyclidine Hydrobromide Phencyclidine Hydrochloride Sernyl Serylan |
| Tree number(s): |
D03.383.621.699 |
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010622 |
| Scope note: | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
| Pharm Action: |
Enzyme Inhibitors Hallucinogens Excitatory Amino Acid Antagonists |
| Registry Number: | J1DOI7UV76 |
| CAS Type 1 Name: | Piperidine, 1-(1-phenylcyclohexyl)- |
| Previous Indexing: |
Anesthetics (1966-1972) Piperidines (1968-1972) |
| Public MeSH Note: | 73; was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967. |
| History Note: | 73(64); was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967 |
| Related: |
Phencyclidine Abuse
MeSH Receptors, Phencyclidine MeSH |
| DeCS ID: | 10812 |
| Unique ID: | D010622 |
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents |
| Date Established: | 1973/01/01 |
| Date of Entry: | 1999/01/01 |
| Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
|
Phencyclidine
- Preferred
GP-121
- Narrower
Serylan
- Narrower
Phencyclidine Hydrochloride
- Narrower
Sernyl
- Narrower
CL-395
- Narrower
Phencyclidine Hydrobromide
- Narrower
| Concept UI |
M0016495 |
| Scope note | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
| Preferred term | Phencyclidine |
| Entry term(s) |
1-(1-Phenylcyclohexyl)piperidine Angel Dust Dust, Angel |
| Concept UI |
M0016496 |
| Preferred term | GP-121 |
| Entry term(s) |
GP 121 GP121 |
| Concept UI |
M0016498 |
| Preferred term | Serylan |
| Concept UI |
M0329830 |
| Preferred term | Phencyclidine Hydrochloride |
| Concept UI |
M0016497 |
| Preferred term | Sernyl |
| Concept UI |
M0373872 |
| Preferred term | CL-395 |
| Entry term(s) |
CL 395 CL395 |
| Concept UI |
M0329829 |
| Preferred term | Phencyclidine Hydrobromide |
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