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Descriptor in English: Transforming Growth Factors
Descriptor in Spanish: Factores de Crecimiento Transformadores
Descriptor in Portuguese: Fatores de Crescimento Transformadores
Descriptor in French: Facteurs de croissance transformants
Entry term(s): Factor, Transforming Growth
Factors, Transforming Growth
Growth Factor, Transforming
Growth Factors, Transforming
Transforming Growth Factor
Tree number(s): D12.644.276.963
D12.776.467.960
D23.529.960
Scope note: Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 89
DeCS UI: 23851
Descriptor UI: D015291
Date Established: 1989/01/01
Date of Entry: 1988/05/24
Revision Date: 2015/06/02
Transforming Growth Factors - Preferred
Concept UI M0023538
Scope note Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
Preferred term Transforming Growth Factors
Entry term(s) Factor, Transforming Growth
Factors, Transforming Growth
Growth Factor, Transforming
Growth Factors, Transforming
Transforming Growth Factor



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