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Descriptor English: Cytochalasins
Descriptor Spanish: Citocalasinas
Descriptor citocalasinas
Scope note: Lactonas macrocíclicas de 11 a 14 miembros con una isoindolona. Los miembros con INDOLES en la posición C10 se llaman quetoglobosinas. Son producidas por diversos hongos. Algunos miembros interactúan con la ACTINA e inhiben la CITOCINESIS.
Descriptor Portuguese: Citocalasinas
Descriptor French: Cytochalasines
Tree number(s): D03.633.100.473.231
D23.946.587.370
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003572
Scope note: 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS.
Annotation: /antag permitted but consider also ANTITOXINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Indoles (1966-1972)
specific fungus (1966-1972)
Public MeSH Note: 74
History Note: 74(73)
DeCS ID: 3590
Unique ID: D003572
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Cytochalasins - Preferred
Concept UI M0005581
Scope note 11- to 14-membered macrocyclic lactones with a fused isoindolone. Members with INDOLES attached at the C10 position are called chaetoglobosins. They are produced by various fungi. Some members interact with ACTIN and inhibit CYTOKINESIS.
Preferred term Cytochalasins



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