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Descriptor English: Inhibitor of Apoptosis Proteins
Descriptor Spanish: Proteínas Inhibidoras de la Apoptosis
Descriptor Portuguese: Proteínas Inibidoras de Apoptose
Descriptor French: Protéines IAP
Entry term(s): Apoptosis Proteins Inhibitor
BIRC2 Protein
Baculoviral IAP Repeat Containing 2 Protein
Baculoviral IAP Repeat Containing Protein 2
Baculoviral IAP Repeat-Containing 2 Protein
Baculoviral Inhibitor Of Apoptosis Repeat Proteins
Cellular Inhibitor of Apoptosis 1 Protein
IAP Protein (Apoptosis)
IAP Repeat Containing Proteins
IAP2 Protein
Inhibitor Of Apoptosis Protein
Inhibitor of Apoptosis 2 Protein
Inhibitor-Of-Apoptosis Protein
c-IAP1 Protein
cIAP1 Protein
Tree number(s): D08.811.464.938.750.210
D12.644.360.075.437
D12.776.476.075.437
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051034
Scope note: A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
Annotation: APOPTOSIS REGULATORY PROTEINS is also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Caspase Inhibitors
Public MeSH Note: 2006; INHIBITOR OF APOPTOSIS PROTEINS was indexed under PROTEINS 1997-2005
History Note: 2006(1997)
DeCS ID: 50802
Unique ID: D051034
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/06/29
Inhibitor of Apoptosis Proteins - Preferred
Concept UI M0283555
Scope note A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
Preferred term Inhibitor of Apoptosis Proteins
Entry term(s) Apoptosis Proteins Inhibitor
Baculoviral Inhibitor Of Apoptosis Repeat Proteins
IAP Protein (Apoptosis)
IAP Repeat Containing Proteins
Inhibitor Of Apoptosis Protein
Inhibitor-Of-Apoptosis Protein
Baculoviral IAP Repeat-Containing 2 Protein - Narrower
Concept UI M0479026
Preferred term Baculoviral IAP Repeat-Containing 2 Protein
Entry term(s) BIRC2 Protein
Baculoviral IAP Repeat Containing 2 Protein
Baculoviral IAP Repeat Containing Protein 2
Cellular Inhibitor of Apoptosis 1 Protein
IAP2 Protein
Inhibitor of Apoptosis 2 Protein
c-IAP1 Protein
cIAP1 Protein



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