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Descriptor English: Fanconi Anemia Complementation Group L Protein
Descriptor Spanish: Proteína del Grupo de Complementación L de la Anemia de Fanconi
Descriptor proteína del grupo de complementación L de la anemia de Fanconi
Scope note: Una UBICUITINA-LIGASA E3 con un papel central en la vía de la respuesta al daño del ADN de las PROTEÍNAS DE LA ANEMIA DE FANCONI. Se asocia a monoubicuitinación de la PROTEÍNA FANCD2 y redistribución de FANCD2 en focos nucleares que contienen PROTEÍNA BRCA1.
Descriptor Portuguese: Proteína do Grupo de Complementação L da Anemia de Fanconi
Descriptor French: Protéine du groupe de complémentation L de l'anémie de Fanconi
Entry term(s): FANCL Protein
Fanconi Anemia Group L Complementing Protein
Fanconi Anemia Group L Protein
PHD Finger Protein 9
Ubiquitin Ligase Protein PHF9
Tree number(s): D08.811.464.938.750.186
D12.776.313.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D052240
Scope note: An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.2.27
Public MeSH Note: 2006; FANCONI ANEMIA COMPLEMENTATION GROUP L PROTEIN was indexed under LIGASES 2003-2005
History Note: 2006 (2003)
DeCS ID: 50585
Unique ID: D052240
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/06/02
Fanconi Anemia Complementation Group L Protein - Preferred
Concept UI M0483809
Scope note An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.
Preferred term Fanconi Anemia Complementation Group L Protein
Entry term(s) FANCL Protein
Fanconi Anemia Group L Complementing Protein
Fanconi Anemia Group L Protein
PHD Finger Protein 9
Ubiquitin Ligase Protein PHF9



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