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Descriptor in English: Emetine
Descriptor in Spanish: Emetina
Descriptor in Portuguese: Emetina
Descriptor in French: Émétine
Entry term(s): Dihydrochloride, Emetine
Emetine Dihydrochloride
Emetine Hydrochloride
Hydrochloride, Emetine
Ipecine
Methylcephaeline
Tree number(s): D03.132.316
D03.633.100.531.321
Scope note: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
DeCS UI: 4715
Descriptor UI: D004640
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/12/08
Emetine - Preferred
Concept UI M0007281
Scope note The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
Preferred term Emetine
Entry term(s) Ipecine
Methylcephaeline
Emetine Hydrochloride - Narrower
Concept UI M0330432
Preferred term Emetine Hydrochloride
Entry term(s) Dihydrochloride, Emetine
Emetine Dihydrochloride
Hydrochloride, Emetine



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