| Descriptor English: | Receptor, Fibroblast Growth Factor, Type 1 | ||||||
| Descriptor Spanish: | 
                                Receptor Tipo 1 de Factor de Crecimiento de Fibroblastos                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Receptor Tipo 1 de Fator de Crescimento de Fibroblastos | ||||||
| Descriptor French: | Récepteur FGFR1 | ||||||
| Entry term(s): | 
                                    Antigen, CD331 CD331 Antigen FGFR1 Protein FGFR1 Tyrosine Kinase Fibroblast Growth Factor Receptor 1 Fibroblast Growth Factor Soluble Receptor 1 fms Like Tyrosine Kinase 2 fms-Like Tyrosine Kinase-2  | 
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| Tree number(s): | 
                                        D08.811.913.696.620.682.725.400.177 D12.776.476.568.400.177 D12.776.543.750.630.440 D12.776.543.750.750.400.370.500  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051496 | ||||||
| Scope note: | A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM. | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure  | 
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| Registry Number: | EC 2.7.10.1 | ||||||
| Public MeSH Note: | 2006; FIBROBLAST GROWTH FACTOR RECEPTOR 1 was indexed under RECEPTORS, FIBROBLAST GROWTH FACTOR & RECEPTOR PROTEIN-TYROSINE KINASES 1994-2005, & under RECEPTORS, ENDOGENOUS SUBSTANCES 1992-1993 | 
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| History Note: | 2006(1992) | 
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| Related: | 
                                                                                                                        Kallmann Syndrome
                                            MeSH                                             | ||||||
| DeCS ID: | 50733 | ||||||
| Unique ID: | D051496 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2017/05/24 | 
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                                        CHEMICALS AND DRUGS
 
Enzymes and Coenzymes [D08]Enzymes and Coenzymes - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins 
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                        Receptor, Fibroblast Growth Factor, Type 1                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Fibroblast Growth Factor Soluble Receptor 1                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0204502 | 
                                
| Scope note | A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM. | 
| Preferred term | Receptor, Fibroblast Growth Factor, Type 1 | 
| Entry term(s) | 
                                        
                                                                                            Antigen, CD331                                                 CD331 Antigen FGFR1 Protein FGFR1 Tyrosine Kinase Fibroblast Growth Factor Receptor 1 fms Like Tyrosine Kinase 2 fms-Like Tyrosine Kinase-2  | 
                                
| Concept UI | 
                                        
                                        M0204500 | 
                                
| Preferred term | Fibroblast Growth Factor Soluble Receptor 1 | 
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