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Descriptor English: Receptor, trkB
Descriptor Spanish: Receptor trkB
Descriptor receptor trkB
Entry term(s) receptor NTRK2
receptor de BDNF
receptor de factor neurotrófico derivado del cerebro
receptor neurotrófico tirosina cinasa tipo 2
Scope note: Receptor proteína tirosina cinasa, específico para el FACTOR NEUROTROFICO DERIVADO DEL CEREBRO, la NEUROTROFINA 3, neurotrofina 4 y neurotrofina 5. Se expresa ampliamente en el tejido nervioso e interviene en la mediación de los efectos de las neurotrofinas en el crecimiento y diferenciación de las meuronas.
Descriptor Portuguese: Receptor trkB
Descriptor French: Récepteur trkB
Entry term(s): BDNF Receptor
Brain Derived Neurotrophic Factor Receptor
NTRK2 Receptor
Neurotrophic Factor, Brain-Derived, Receptor
Neurotrophic Tyrosine Kinase Receptor Type 2
Receptor, BDNF
Receptor, NTRK2
Receptor, Neurotrophic Tyrosine Kinase Type 2
trkB Receptor
trkB(gp145) Protein
Tree number(s): D08.811.913.696.620.682.725.400.700
D12.776.476.568.400.700
D12.776.543.750.630.498
D12.776.543.750.750.400.550.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020813
Scope note: A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.10.1
Previous Indexing: Membrane Glycoproteins (1990-1993)
Protein-Tyrosine Kinase (1990-1993)
Receptor Protein-Tyrosine Kinase (1994-1999)
Receptors, Growth Factor (1990-1993)
Receptors, Nerve Growth Factor (1994-1999)
Public MeSH Note: 2000; TRKB(GP145) PROTEIN was indexed under RECEPTORS, NERVE GROWTH FACTOR & RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999, and under MEMBRANE GLYCOPROTEINS, PROTEIN-TYROSINE KINASE & RECEPTORS, GROWTH FACTOR 1990-1999; BDNF RECEPTOR was indexed under RECEPTORS, NERVE GROWTH FACTOR & RECEPTOR PROTEIN-TYROSINE KINASE 1995-1999
History Note: 2000; for TRKB(GP145) PROTEIN use RECEPTOR, TYPE 2 NEUROTROPHIC TYROSINE KINASE (NM) 1990-1999; for BDNF RECEPTOR use RECEPTOR, TYPE 2 NEUROTROPHIC TYROSINE KINASE (NM) 1995-1999
Entry Version: RECEPT TRKB
DeCS ID: 34456
Unique ID: D020813
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2016/05/31
Receptor, trkB - Preferred
Concept UI M0328269
Scope note A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.
Preferred term Receptor, trkB
Entry term(s) BDNF Receptor
Brain Derived Neurotrophic Factor Receptor
NTRK2 Receptor
Neurotrophic Factor, Brain-Derived, Receptor
Neurotrophic Tyrosine Kinase Receptor Type 2
Receptor, BDNF
Receptor, NTRK2
Receptor, Neurotrophic Tyrosine Kinase Type 2
trkB Receptor
trkB(gp145) Protein



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