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Descriptor English: Rimonabant
Descriptor Spanish: Rimonabant
Descriptor rimonabant
Entry term(s) SR 141716
SR 141716A
SR-141716A
SR141716
SR141716A
acomplia
hidrocloruro de N-(piperidin-1-il)-5-(4-clorofenil)-1-(2,4-diclorofenil)-4-metil-1H-pirazol-3-carboxamida
hidrocloruro de rimonabant
zimulti
Scope note: Derivado pirazólico y piperidínico que actúa como antagonista selectivo de los receptores de cannabinoides de tipo 1 (RECEPTOR CB1). Inhibe la proliferación y la maduración de los ADIPOCITOS, mejora el metabolismo de los lípidos y de la glucosa y regula la ingesta alimentaria y el balance energético. Se usa en el tratamiento de la OBESIDAD.
Descriptor Portuguese: Rimonabanto
Descriptor French: Rimonabant
Entry term(s): Chlorhydrate de rimonabant
SR-141716
SR-141716A
SR141716
SR141716A
Tree number(s): D03.383.129.539.888
D03.383.621.834
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077285
Scope note: A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Obesity Agents
Cannabinoid Receptor Antagonists
Registry Number: RML78EN3XE
CAS Type 1 Name: 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-
DeCS ID: 57586
Unique ID: D000077285
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Rimonabant - Preferred
Concept UI M0235470
Preferred term Rimonabant
SR-141716 - Narrower
Concept UI M0445880
Preferred term SR-141716
Entry term(s) SR141716
Chlorhydrate de rimonabant - Narrower
Concept UI M000640319
Preferred term Chlorhydrate de rimonabant
SR-141716A - Narrower
Concept UI M0235474
Preferred term SR-141716A
Entry term(s) SR141716A



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