| Descriptor English: | Prothrombin | ||||||
| Descriptor Spanish: |
Protrombina
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| Descriptor Portuguese: | Protrombina | ||||||
| Descriptor French: | Prothrombine | ||||||
| Entry term(s): |
Blood Coagulation Factor II Coagulation Factor II Differentiation Reversal Factor Factor II Factor II, Coagulation Factor, Differentiation Reversal II, Coagulation Factor |
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| Tree number(s): |
D08.622.709 D12.776.124.125.800 D12.776.811.243.709 D23.119.945 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011516 | ||||||
| Scope note: | A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia. |
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| Annotation: | a blood coag factor; an enzyme precursor |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
deficiency:Hypoprothrombinemias
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| Registry Number: | 9001-26-7 | ||||||
| CAS Type 1 Name: | Blood-coagulation factor II | ||||||
| Related: |
Coagulants
MeSH | ||||||
| DeCS ID: | 22270 | ||||||
| Unique ID: | D011516 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2005/06/30 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Prothrombin
- Preferred
| Concept UI |
M0017904 |
| Scope note | A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia. |
| Preferred term | Prothrombin |
| Entry term(s) |
Blood Coagulation Factor II Coagulation Factor II Differentiation Reversal Factor Factor II Factor II, Coagulation Factor, Differentiation Reversal II, Coagulation Factor |
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