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Descriptor English: Ubiquitin-Protein Ligases
Descriptor Spanish: Ubiquitina-Proteína Ligasas
Descriptor ubicuitina-proteína ligasas
Entry term(s) ligasa E3
ubicuitina-proteína ligasa
ubiquitina-proteína ligasa
ubiquitina-proteína ligasas
Scope note: Clase diversa de enzimas que interactúan con las ENZIMAS DE CONJUGACIÓN DE LA UBICUITINA y sustratos proteicos específicos de la ubicuitinación. Cada miembro de este grupo de enzimas tiene su propia y diferente especificidad por un sustrato y una enzima de conjugación de la ubicuitina. Las ubicuitina-proteína ligasas existen como proteínas monoméricas y como complejos multiproteicos.
Descriptor Portuguese: Ubiquitina-Proteína Ligases
Descriptor French: Ubiquitin-protein ligases
Entry term(s): E3 Ligase
E3 Ubiquitin Ligase
Ligase E3, Ubiquitin
Ligase E3, Ubiquitin-Protein
Ligase, E3
Ligase, E3 Ubiquitin
Ligase, Ubiquitin-Protein
Ligases, Ubiquitin-Protein
Ubiquitin Ligase E3
Ubiquitin Ligase, E3
Ubiquitin Protein Ligase
Ubiquitin Protein Ligase E3
Ubiquitin Protein Ligases
Ubiquitin-Protein Ligase
Ubiquitin-Protein Ligase E3
Tree number(s): D08.811.464.938.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044767
Scope note: A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
Annotation: UBIQUITIN-PROTEIN LIGASE COMPLEXES is also available
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.2.27
Previous Indexing: Ligases (1983-2003)
Public MeSH Note: 2004; UBIQUITIN-PROTEIN LIGASE was indexed under LIGASES 1983-2003; E3 UBIQUITIN LIGASE was indexed under LIGASES 1993-2003
History Note: 2004; use UBIQUITIN-PROTEIN LIGASE (NM) 1983-2003
DeCS ID: 38183
Unique ID: D044767
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/02
Ubiquitin-Protein Ligases - Preferred
Concept UI M0446168
Scope note A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
Preferred term Ubiquitin-Protein Ligases
Entry term(s) E3 Ligase
E3 Ubiquitin Ligase
Ligase E3, Ubiquitin
Ligase E3, Ubiquitin-Protein
Ligase, E3
Ligase, E3 Ubiquitin
Ligase, Ubiquitin-Protein
Ligases, Ubiquitin-Protein
Ubiquitin Ligase E3
Ubiquitin Ligase, E3
Ubiquitin Protein Ligase
Ubiquitin Protein Ligase E3
Ubiquitin Protein Ligases
Ubiquitin-Protein Ligase
Ubiquitin-Protein Ligase E3



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