| Descriptor English: | Wnt-5a Protein | ||||||
| Descriptor Spanish: |
Proteína Wnt-5a
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| Descriptor Portuguese: | Proteína Wnt-5a | ||||||
| Descriptor French: | Protéine Wnt-5a | ||||||
| Entry term(s): |
Wingless Type MMTV Integration Site Family, Member 5A Wingless-Type MMTV Integration Site Family, Member 5A Wnt 5a Protein Wnt5a Protein |
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| Tree number(s): |
D12.776.467.984.050 D12.776.624.664.700.962 D23.529.984.050 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071818 | ||||||
| Scope note: | A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Proto-Oncogene Proteins (1994-2016) Wnt Proteins (2006-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56635 | ||||||
| Unique ID: | D000071818 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/04/15 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Wnt-5a Protein
- Preferred
| Concept UI |
M000615554 |
| Scope note | A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells. |
| Preferred term | Wnt-5a Protein |
| Entry term(s) |
Wingless Type MMTV Integration Site Family, Member 5A Wingless-Type MMTV Integration Site Family, Member 5A Wnt 5a Protein Wnt5a Protein |
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