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Descriptor English: RANK Ligand
Descriptor Spanish: Ligando RANK
Descriptor ligando RANK
Entry term(s) miembro 11 de la superfamilia de ligandos del factor de necrosis tumoral
Scope note: Proteína transmembranaria que pertenece a la superfamilia de los factores de necrosis tumoral que une de modo específico el ACTIVADOR DEL RECEPTOR DEL FACTOR NUCLEAR KAPPA B y la OSTEOPROTEGERINA. Desempeña un papel importante en la regulación de la diferenciación y activación de los OSTEOCLASTOS.
Descriptor Portuguese: Ligante RANK
Descriptor French: Ligand de RANK
Entry term(s): Antigen, CD254
CD254 Antigen
Differentiation Factor, Osteoclast
OPGL Protein
Osteoclast Differentiation Factor
Osteoprotegerin Ligand
RANKL Protein
Receptor Activator of Nuclear Factor kappa B Ligand
Receptor Activator of Nuclear Factor kappaB Ligand
Receptor Activator of Nuclear Factor-kappa B Ligand
Receptor Activator of Nuclear Factor-kappaB Ligand
TNF Superfamily, Member 11
TRANCE Protein
Tumor Necrosis Factor Ligand Superfamily Member 11
Tumor Necrosis Factor Related Activation Induced Cytokine
Tumor Necrosis Factor-Related Activation-Induced Cytokine
Tree number(s): D12.644.276.374.750.562
D12.776.467.374.750.562
D23.529.374.750.562
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053245
Scope note: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; RANK LIGAND was indexed under CARRIER PROTEINS & MEMBRANE GLYCOPROTEINS 1997-2006
History Note: 2007(1997)
Related: Denosumab MeSH
DeCS ID: 52297
Unique ID: D053245
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/31
RANK Ligand - Preferred
Concept UI M0281676
Scope note A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
Preferred term RANK Ligand
Entry term(s) Antigen, CD254
CD254 Antigen
Differentiation Factor, Osteoclast
OPGL Protein
Osteoclast Differentiation Factor
Osteoprotegerin Ligand
RANKL Protein
Receptor Activator of Nuclear Factor kappa B Ligand
Receptor Activator of Nuclear Factor kappaB Ligand
Receptor Activator of Nuclear Factor-kappa B Ligand
Receptor Activator of Nuclear Factor-kappaB Ligand
TNF Superfamily, Member 11
TRANCE Protein
Tumor Necrosis Factor Ligand Superfamily Member 11
Tumor Necrosis Factor Related Activation Induced Cytokine
Tumor Necrosis Factor-Related Activation-Induced Cytokine



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