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Descriptor English: 4-1BB Ligand
Descriptor Spanish: Ligando 4-1BB
Descriptor Portuguese: Ligante 4-1BB
Descriptor French: Ligand de 4-1BB
Entry term(s): 4 1BB Ligand
4 1BBL Protein
4-1BBL Protein
CD137 Ligand
Tumor Necrosis Factor (Ligand) Superfamily, Member 9
Tumor Necrosis Factor Ligand Superfamily Member 9
Tree number(s): D12.644.276.374.750.065
D12.776.395.192
D12.776.467.374.750.065
D12.776.543.550.194
D23.529.374.750.065
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053330
Scope note: A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; 4-1BB LIGAND was indexed under TUMOR NECROSIS FACTORS 2006 & under TUMOR NECROSIS FACTOR-ALPHA 1998-2005
History Note: 2007(1998)
DeCS ID: 52290
Unique ID: D053330
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/06/22
4-1BB Ligand - Preferred
Concept UI M0291679
Scope note A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
Preferred term 4-1BB Ligand
Entry term(s) 4 1BB Ligand
4 1BBL Protein
4-1BBL Protein
CD137 Ligand
Tumor Necrosis Factor (Ligand) Superfamily, Member 9
Tumor Necrosis Factor Ligand Superfamily Member 9



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