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Descriptor English: B-Cell Activating Factor
Descriptor Spanish: Factor Activador de Células B
Descriptor factor activador de células B
Entry term(s) antígenos CD257
factor activador de linfocitos B
ligando BAFF
miembro 13b de la superfamilia de ligandos del factor de necrosis tumoral
Scope note: Miembro de la superfamilia de factores de necrosis tumoral que desempeña un papel en la regulación de la supervivencia de los LINFOCITOS B. Se da como proteína unida a la membrana que es desdoblada para liberar una forma soluble biológicamente activa con especificidad por la PROTEÍNA ACTIVADORA TRANSMEMBRANA E INTERACTORA CAML, por el RECEPTOR DEL FACTOR ACTIVADOR DE CÉLULAS B, y por el ANTÍGENO DE MADURACIÓN DE LAS CÉLULAS B.
Descriptor Portuguese: Fator Ativador de Células B
Descriptor French: Facteur d'activation des lymphocytes B
Entry term(s): Activating Factor, B-Cell
Activating Factor, B-Lymphocyte
Antigen, CD257
Antigens, CD257
B Cell Activating Factor
B Lymphocyte Activating Factor
B Lymphocyte Stimulator
B-Lymphocyte Activating Factor
BAFF Ligand
BLyS Protein
CD257 Antigen
CD257 Antigens
TALL 1 Protein
TALL-1 Protein
THANK Protein
TNF Superfamily, Member 13b
TNF and APOL Related Leukocyte Expressed Ligand 1
TNF and APOL-Related Leukocyte Expressed Ligand 1
TNFSF13B Protein
Tumor Necrosis Factor Ligand Superfamily Member 13b
Tree number(s): D09.400.430.681
D12.644.276.374.750.061
D12.776.395.191
D12.776.467.374.750.061
D12.776.543.550.193
D23.529.374.750.061
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053264
Scope note: A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; B-CELL ACTIVATING FACTOR was indexed under TUMOR NECROSIS FACTOR ALPHA & MEMBRANE PROTEINS 1999-2006
History Note: 2007(1999)
DeCS ID: 52289
Unique ID: D053264
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
B-Cell Activating Factor - Preferred
Concept UI M0305108
Scope note A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
Preferred term B-Cell Activating Factor
Entry term(s) Activating Factor, B-Cell
Activating Factor, B-Lymphocyte
Antigen, CD257
Antigens, CD257
B Cell Activating Factor
B Lymphocyte Activating Factor
B Lymphocyte Stimulator
B-Lymphocyte Activating Factor
BAFF Ligand
BLyS Protein
CD257 Antigen
CD257 Antigens
TALL 1 Protein
TALL-1 Protein
THANK Protein
TNF Superfamily, Member 13b
TNF and APOL Related Leukocyte Expressed Ligand 1
TNF and APOL-Related Leukocyte Expressed Ligand 1
TNFSF13B Protein
Tumor Necrosis Factor Ligand Superfamily Member 13b



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