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Descriptor English: CD40 Ligand
Descriptor Spanish: Ligando de CD40
Descriptor Portuguese: Ligante de CD40
Descriptor French: Ligand de CD40
Entry term(s): Antigen, CD154
Antigens, CD154
CD154 Antigen
CD154 Antigens
CD40L
T-B Cell Activating Molecule
T-Cell gp39 Antigen
TNF Superfamily, Member 5
Tumor Necrosis Factor Ligand Superfamily Member 5
gp39 Antigen, T Cell
gp39 Antigen, T-Cell
Tree number(s): D12.644.276.374.750.124
D12.776.395.550.185
D12.776.467.374.750.124
D12.776.543.550.198
D23.529.374.750.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D023201
Scope note: A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 147205-72-9
Previous Indexing: Membrane Glycoproteins (1992-2000)
Public MeSH Note: 2001; CD40 LIGAND was indexed under MEMBRANE GLYCOPROTEINS 1992-2000
History Note: 2001(2000)
Related: CD40 Antigens MeSH
DeCS ID: 35344
Unique ID: D023201
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2001/01/01
Date of Entry: 2000/06/23
Revision Date: 2017/05/24
CD40 Ligand - Preferred
Concept UI M0200619
Scope note A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.
Preferred term CD40 Ligand
Entry term(s) Antigen, CD154
Antigens, CD154
CD154 Antigen
CD154 Antigens
CD40L
T-B Cell Activating Molecule
T-Cell gp39 Antigen
TNF Superfamily, Member 5
Tumor Necrosis Factor Ligand Superfamily Member 5
gp39 Antigen, T Cell
gp39 Antigen, T-Cell



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