| Descriptor English: | TNF-Related Apoptosis-Inducing Ligand | ||||||
| Descriptor Spanish: |
Ligando Inductor de Apoptosis Relacionado con TNF
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| Descriptor Portuguese: | Ligante Indutor de Apoptose Relacionado a TNF | ||||||
| Descriptor French: | Ligand TRAIL | ||||||
| Entry term(s): |
Antigen, CD253 Apo 2 Ligand Apo 2L Protein Apo-2 Ligand Apo-2L Protein Apoptosis-Inducing Ligand, TNF-Related CD253 Antigen TNF Related Apoptosis Inducing Ligand TNF Superfamily, Member 10 TRAIL Protein Tumor Necrosis Factor Ligand Superfamily Member 10 |
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| Tree number(s): |
D12.644.276.374.750.625 D12.776.467.374.750.625 D23.529.374.750.625 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053221 | ||||||
| Scope note: | A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2007; TNF-RELATED APOPTOSIS-INDUCING LIGAND was indexed under APOPTOSIS REGULATORY PROTEINS, TUMOR NECROSIS FACTOR-ALPHA and MEMBRANE GLYCOPROTEINS 1996-2006 |
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| History Note: | 2007(2005) |
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| DeCS ID: | 52298 | ||||||
| Unique ID: | D053221 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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TNF-Related Apoptosis-Inducing Ligand
- Preferred
| Concept UI |
M0256022 |
| Scope note | A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. |
| Preferred term | TNF-Related Apoptosis-Inducing Ligand |
| Entry term(s) |
Antigen, CD253 Apo 2 Ligand Apo 2L Protein Apo-2 Ligand Apo-2L Protein Apoptosis-Inducing Ligand, TNF-Related CD253 Antigen TNF Related Apoptosis Inducing Ligand TNF Superfamily, Member 10 TRAIL Protein Tumor Necrosis Factor Ligand Superfamily Member 10 |
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