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Descriptor English: Fas Ligand Protein
Descriptor Spanish: Proteína Ligando Fas
Descriptor Portuguese: Proteína Ligante Fas
Descriptor French: Ligand de Fas
Entry term(s): Antigen, CD178
Antigens, CD178
CD178 Antigen
CD178 Antigens
CD95 Antigen Ligand
CD95 Ligand
CD95L
Fas Ligand
Fas Ligand (FasL)
FasL Protein
TNF Superfamily, Member 6
Tumor Necrosis Factor Ligand Superfamily Member 6
Tree number(s): D12.644.276.374.750.249
D12.776.395.550.312
D12.776.467.374.750.249
D12.776.543.550.312
D23.529.374.750.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053222
Scope note: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; FAS LIGAND PROTEIN was indexed under TUMOR NECROSIS FACTORS and MEMBRANE GLYCOPROTEINS 1994-2006
History Note: 2007(1994)
DeCS ID: 52293
Unique ID: D053222
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Fas Ligand Protein - Preferred
Concept UI M0229054
Scope note A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
Preferred term Fas Ligand Protein
Entry term(s) Antigen, CD178
Antigens, CD178
CD178 Antigen
CD178 Antigens
CD95 Antigen Ligand
CD95 Ligand
CD95L
Fas Ligand
Fas Ligand (FasL)
FasL Protein
TNF Superfamily, Member 6
Tumor Necrosis Factor Ligand Superfamily Member 6



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