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Descriptor English: CD27 Ligand
Descriptor Spanish: Ligando CD27
Descriptor Portuguese: Ligante CD27
Descriptor French: Antigènes CD70
Entry term(s): Antigen, CD70
Antigens, CD70
CD27L Protein
CD70 Antigen
CD70 Antigens
Ligand, CD27
TNF Superfamily, Member 7
Tumor Necrosis Factor Ligand Superfamily Member 7
Tree number(s): D12.644.276.374.750.030
D12.776.395.092
D12.776.467.374.750.030
D12.776.543.550.170
D23.529.374.750.030
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053282
Scope note: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS where it plays a role in stimulating the proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2018; see ANTIGENS, CD70 2007-2017; CD27 LIGAND was indexed under ANTIGENS, CD; MEMBRANE PROTEINS; and TUMOR NECROSIS FACTORS 1993-2006
History Note: 2018 (1993)
DeCS ID: 52288
Unique ID: D053282
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
CD27 Ligand - Preferred
Concept UI M0216394
Scope note A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS where it plays a role in stimulating the proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES.
Preferred term CD27 Ligand
Entry term(s) Antigen, CD70
Antigens, CD70
CD27L Protein
CD70 Antigen
CD70 Antigens
Ligand, CD27
TNF Superfamily, Member 7
Tumor Necrosis Factor Ligand Superfamily Member 7



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