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Descriptor English: | CLOCK Proteins | ||||
Descriptor Spanish: |
Proteínas CLOCK
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Descriptor Portuguese: | Proteínas CLOCK | ||||
Descriptor French: | Protéines CLOCK | ||||
Entry term(s): |
Circadian Locomoter Output Cycles Kaput Proteins Protéines horloges |
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Tree number(s): |
D08.811.913.050.134.415.500.049 D12.644.360.138.100 D12.776.260.103.562 D12.776.476.156.200 D12.776.930.125.562 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D056926 | ||||
Scope note: | Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins. |
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Allowable Qualifiers: |
AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BI biosynthèse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique DE effets des médicaments et des substances chimiques DF déficit EC économie GE génétique HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PH physiologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UL ultrastructure UR urine |
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Registry Number: | EC 2.3.1.48 | ||||
DeCS ID: | 53609 | ||||
Unique ID: | D056926 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 2010/01/01 | ||||
Date of Entry: | 2009/07/06 | ||||
Revision Date: | 2018/06/30 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Enzymes et coenzymes [D08]Enzymes et coenzymes -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides aminés, peptides et protéines [D12]Acides aminés, peptides et protéines -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides aminés, peptides et protéines [D12]Acides aminés, peptides et protéines -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides aminés, peptides et protéines [D12]Acides aminés, peptides et protéines -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides aminés, peptides et protéines [D12]Acides aminés, peptides et protéines
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Protéines CLOCK
- Preferred
Concept UI |
M0533475 |
Preferred term | Protéines CLOCK |
Entry term(s) |
Circadian Locomoter Output Cycles Kaput Proteins Protéines horloges |
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