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Descriptor English: Proto-Oncogene Proteins c-myc
Descriptor Spanish: Proteínas Proto-Oncogénicas c-myc
Descriptor proteínas protooncogénicas c-myc
Entry term(s) proteínas c-myc
proteínas de protooncogén c-myc
proteínas l-myc
Scope note: Factores de transcripción con hélice-asa-hélice básica codificados por los genes c-myc. Normalmente participan en el metabolismo de los ácidos nucleicos y median la respuesta celular a los factores de crecimiento. La expresión elevada y no regulada (constitutiva) de las proteínas c-myc pueden causar tumorigénesis.
Descriptor Portuguese: Proteínas Proto-Oncogênicas c-myc
Descriptor French: Protéines proto-oncogènes c-myc
Entry term(s): L myc Proteins
L-myc Proteins
N myc Proteins
N-myc Proteins
Proteins myc, Proto-Oncogene
Proto Oncogene Products c myc
Proto Oncogene Proteins c myc
Proto Oncogene Proteins myc
Proto-Oncogene Products c-myc
Proto-Oncogene Proteins myc
Proto-Oncogene Proteins, myc
c myc Proteins
c-myc Proteins
myc Proto Oncogene Product p62
myc Proto Oncogene Proteins
myc Proto-Oncogene Product p62
myc Proto-Oncogene Proteins
myc, Proto-Oncogene Proteins
p62 c myc
p62 c-myc
p62(c-myc)
Tree number(s): D12.776.260.103.813
D12.776.624.664.700.189
D12.776.660.765
D12.776.930.125.813
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016271
Scope note: Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Neoplasm Proteins (1983-1984)
Phosphoproteins (1985)
Proto-Oncogene Proteins (1986-1990)
Public MeSH Note: 91
History Note: 91
DeCS ID: 29093
Unique ID: D016271
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/19
Revision Date: 2018/07/01
Proto-Oncogene Proteins c-myc - Preferred
Concept UI M0024867
Scope note Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
Preferred term Proto-Oncogene Proteins c-myc
Entry term(s) Proteins myc, Proto-Oncogene
Proto Oncogene Products c myc
Proto Oncogene Proteins c myc
Proto Oncogene Proteins myc
Proto-Oncogene Products c-myc
Proto-Oncogene Proteins myc
Proto-Oncogene Proteins, myc
c myc Proteins
c-myc Proteins
myc Proto Oncogene Product p62
myc Proto Oncogene Proteins
myc Proto-Oncogene Product p62
myc Proto-Oncogene Proteins
myc, Proto-Oncogene Proteins
p62 c myc
p62 c-myc
p62(c-myc)
N-myc Proteins - Related but not broader or narrower
Concept UI M0024866
Preferred term N-myc Proteins
Entry term(s) N myc Proteins
L-myc Proteins - Related but not broader or narrower
Concept UI M0024865
Preferred term L-myc Proteins
Entry term(s) L myc Proteins



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