Descriptor English: | p300-CBP Transcription Factors | ||||
Descriptor Spanish: |
Factores de Transcripción p300-CBP
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Descriptor Portuguese: | Fatores de Transcrição de p300-CBP | ||||
Descriptor French: | Facteurs de transcription CBP-p300 | ||||
Entry term(s): |
Coactivator, p300-CBP Transcription Factors, p300-CBP p300 CBP Coactivator p300 CBP Protein p300 CBP Transcription Factors p300-CBP Coactivator p300-CBP Protein |
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Tree number(s): |
D08.811.913.050.134.415.500.575 D12.776.930.680 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050880 | ||||
Scope note: | A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.3.1.48 | ||||
Public MeSH Note: | 2006; P300/CBP PROTEINS was indexed under NUCLEAR PROTEINS & TRANS-ACTIVATORS 1999-2005 |
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History Note: | 2006(1994) |
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DeCS ID: | 50671 | ||||
Unique ID: | D050880 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 2006/01/01 | ||||
Date of Entry: | 2005/06/30 | ||||
Revision Date: | 2015/12/02 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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p300-CBP Transcription Factors
- Preferred
Concept UI |
M0232680 |
Scope note | A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION. |
Preferred term | p300-CBP Transcription Factors |
Entry term(s) |
Coactivator, p300-CBP Transcription Factors, p300-CBP p300 CBP Coactivator p300 CBP Protein p300 CBP Transcription Factors p300-CBP Coactivator p300-CBP Protein |
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