Search
Descriptor English: Cholesterol 24-Hydroxylase
Descriptor Spanish: Colesterol 24-Hidroxilasa
Descriptor colesterol 24-hidroxilasa
Entry term(s) 24S-hidroxilasa específica del cerebro
5(beta)-colestano-3 alfa,7 alfa,12 alfa,25-tetrol-24S-hidroxilasa
CYP46A1
citocromo P450 46A1
colestano tetrol 24-hidroxilasa
Scope note: Hidroxilasa esteroidea que actúa en la homeostasis del COLESTEROL en el cerebro. Convierte el colesterol en 24-hidroxicolesterol que es transportado a través de la BARRERA HEMATOENCEFÁLICA más rápidamente que el colesterol no metabolizado.
Descriptor Portuguese: Colesterol 24-Hidroxilase
Descriptor French: Cholesterol 24-hydroxylase
Entry term(s): 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Brain Specific 24S Hydroxylase
Brain-Specific 24S-Hydroxylase
CYP46A1
Cholestane Tetrol 24 Hydroxylase
Cholestane Tetrol 24-Hydroxylase
Cholesterol 24 Hydroxylase
Cytochrome P450 46A1
Tree number(s): D08.244.453.875.500
D08.244.453.915.025
D08.811.682.690.708.170.497.500
D08.811.682.690.708.170.915.025
D12.776.422.220.453.875.500
D12.776.422.220.453.915.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072556
Scope note: A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.14.25
Public MeSH Note: 2017; CHOLESTEROL 24-HYDROXYLASE was indexed under STEROID HYDROXYLASES 1999-2016
History Note: 2017 (1999)
DeCS ID: 56451
Unique ID: D000072556
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/06/01
Cholesterol 24-Hydroxylase - Preferred
Concept UI M0333121
Scope note A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
Preferred term Cholesterol 24-Hydroxylase
Entry term(s) Brain Specific 24S Hydroxylase
Brain-Specific 24S-Hydroxylase
Cholesterol 24 Hydroxylase
Cholestane Tetrol 24-Hydroxylase - Narrower
Concept UI M0072868
Preferred term Cholestane Tetrol 24-Hydroxylase
Entry term(s) 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Cholestane Tetrol 24 Hydroxylase
Cytochrome P450 46A1 - Narrower
Concept UI M000617278
Preferred term Cytochrome P450 46A1
Entry term(s) CYP46A1



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey