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Descriptor English: Cystatins
Descriptor Spanish: Cistatinas
Descriptor cistatinas
Entry term(s) cistatina
estefina
superfamilia de cistatinas
Scope note: Grupo homólogo de INHIBIDORES DE CISTEÍNA PROTEINASA endógenos. Las cistatinas inhiben a la mayoría de las CISTEÍNA ENDOPEPTIDASAS, como la PAPAÍNA, y a otras peptidasas que tienen un grupo sulfhidrilo en el sitio activo.
Descriptor Portuguese: Cistatinas
Descriptor French: Cystatines
Entry term(s): Cystatin
Cystatin Related Proteins
Cystatin Superfamily
Cystatin-Related Proteins
Cystatins, Type 1
Cystatins, Type 2
Cystatins, Type 3
Cystatins, Type I
Cystatins, Type II
Cystatins, Type III
Stefin
Stefins
Type 1 Cystatins
Type 2 Cystatins
Type 3 Cystatins
Type I Cystatins
Type II Cystatins
Type III Cystatins
Tree number(s): D12.776.215
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015891
Scope note: A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Cysteine Proteinase Inhibitors
Previous Indexing: Enzyme Inhibitors (1975-1978)
Protease Inhibitors (1979-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24594
Unique ID: D015891
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2020/05/27
Cystatins - Preferred
Concept UI M0024322
Scope note A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
Preferred term Cystatins
Entry term(s) Cystatin
Cystatin Superfamily
Type 3 Cystatins - Narrower
Concept UI M0517013
Scope note Cystatins that occur as plasma proteins.
Preferred term Type 3 Cystatins
Entry term(s) Cystatins, Type 3
Cystatins, Type III
Type III Cystatins
Type 2 Cystatins - Narrower
Concept UI M0517012
Scope note Cystatins that occur primarily as extracellular proteins.
Preferred term Type 2 Cystatins
Entry term(s) Cystatins, Type 2
Cystatins, Type II
Type II Cystatins
Cystatin-Related Proteins - Related but not broader or narrower
Concept UI M0517011
Preferred term Cystatin-Related Proteins
Entry term(s) Cystatin Related Proteins
Type 1 Cystatins - Narrower
Concept UI M0516521
Scope note Cystatins that occur primarily as intracellular proteins.
Preferred term Type 1 Cystatins
Entry term(s) Cystatins, Type 1
Cystatins, Type I
Stefin
Stefins
Type I Cystatins



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