| Descriptor English: | Intrinsically Disordered Proteins | ||||||
| Descriptor Spanish: |
Proteínas Intrínsecamente Desordenadas
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| Descriptor Portuguese: | Proteínas Intrinsicamente Desordenadas | ||||||
| Descriptor French: | Protéines intrinsèquement désordonnées | ||||||
| Entry term(s): |
Disordered Protein, Intrinsically Intrinsically Disordered Protein Natively Unfolded Protein Natively Unfolded Proteins Protein, Intrinsically Disordered Protein, Natively Unfolded Protein, Unstructured Unfolded Protein, Natively Unstructured Protein Unstructured Proteins |
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| Tree number(s): |
D12.776.481 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064267 | ||||||
| Scope note: | Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2014 |
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| History Note: | 2014 |
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| Related: |
Protein Folding
MeSH Protein Unfolding MeSH | ||||||
| DeCS ID: | 55331 | ||||||
| Unique ID: | D064267 | ||||||
| NLM Classification: | QU 55 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 | ||||||
| Revision Date: | 2020/06/29 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Intrinsically Disordered Proteins
- Preferred
| Concept UI |
M0580703 |
| Scope note | Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions. |
| Preferred term | Intrinsically Disordered Proteins |
| Entry term(s) |
Disordered Protein, Intrinsically Intrinsically Disordered Protein Natively Unfolded Protein Natively Unfolded Proteins Protein, Intrinsically Disordered Protein, Natively Unfolded Protein, Unstructured Unfolded Protein, Natively Unstructured Protein Unstructured Proteins |
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