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Descriptor in English: Thioredoxins
Descriptor in Spanish: Tiorredoxinas
Descriptor in Portuguese: Tiorredoxinas
Descriptor in French: Thiorédoxines
Entry term(s): Thioredoxin
Thioredoxin 1
Thioredoxin 2
Thioredoxin-1
Thioredoxin-2
Tree number(s): D12.776.915
Scope note: Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2008(1975)
DeCS UI: 14264
Descriptor UI: D013879
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2007/07/09
Thioredoxins - Preferred
Concept UI M0021373
Scope note Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Preferred term Thioredoxins
Entry term(s) Thioredoxin
Thioredoxin 2 - Narrower
Concept UI M0470017
Preferred term Thioredoxin 2
Entry term(s) Thioredoxin-2
Thioredoxin 1 - Narrower
Concept UI M0505373
Preferred term Thioredoxin 1
Entry term(s) Thioredoxin-1



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