Search
Descriptor English: Endothelins
Descriptor Spanish: Endotelinas
Descriptor endotelinas
Entry term(s) factores vasconstrictores derivados del endotelio
Scope note: Péptidos de 21 aminoácidos producidos por las células del endotelio vascular que funcionan como potentes vasoconstrictores. La familia de las endotelinas consta de tres miembros, ENDOTELINA 1, ENDOTELINA 2 Y ENDOTELINA 3. Los tres péptidos contienen 21 aminoácidos pero varían en su composición de aminoácidos. Los tres péptidos producen respuestas vasoconstrictoras y presoras en diversas partes del organismo. Sin embargo, los perfiles cuantitativos de las actividades farmacológicas son considerablemente diferentes entre los tres isopéptidos.
Descriptor Portuguese: Endotelinas
Descriptor French: Endothélines
Entry term(s): Endothelin
Endothelium-Derived Vasoconstrictor Factors
Vasoconstrictor Factors, Endothelium-Derived
Tree number(s): D12.644.276.400
D12.776.467.400
D23.529.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016232
Scope note: 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Peptides (1966-1990)
Public MeSH Note: 91
History Note: 91
Related: Receptors, Endothelin MeSH
DeCS ID: 28921
Unique ID: D016232
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/28
Revision Date: 2006/07/05
Endothelins - Preferred
Concept UI M0024788
Scope note 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
Preferred term Endothelins
Entry term(s) Endothelin
Endothelium-Derived Vasoconstrictor Factors
Vasoconstrictor Factors, Endothelium-Derived



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey