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Descriptor English: Lac Repressors
Descriptor Spanish: Represoras Lac
Descriptor represores lac
Scope note: Proteínas bacterianas represoras que se unen al OPERÓN LAC y, por lo tanto, previenen la síntesis de las proteínas implicadas en el catabolismo de la LACTOSA. Cuando las concentraciones de lactosa están elevadas los represores sufren un cambio alostérico que causa su liberación del ADN y la reanudación de la transcripción del operón lac.
Descriptor Portuguese: Repressores Lac
Descriptor French: Répresseurs lac
Entry term(s): Lac Repressor
LacI Proteins
Proteins, LacI
Repressor, Lac
Repressors, Lac
Tree number(s): D12.776.097.521
D12.776.260.703.600
D12.776.930.780.781
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056968
Scope note: Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; see REPRESSOR PROTEINS 1979-2009
History Note: 2010; use REPRESSOR PROTEINS 1979-2009
DeCS ID: 53637
Unique ID: D056968
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/06/29
Lac Repressors - Preferred
Concept UI M0018808
Scope note Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.
Preferred term Lac Repressors
Entry term(s) Lac Repressor
LacI Proteins
Proteins, LacI
Repressor, Lac
Repressors, Lac



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