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Descriptor English: Fibroblast Growth Factors
Descriptor Spanish: Factores de Crecimiento de Fibroblastos
Descriptor factores de crecimiento de fibroblastos
Scope note: Familia de factores de crecimiento de pequeños polipéptidos que comparten varios rasgos comunes, como son una gran afinidad por la HEPARINA, una región central toneliforme de 140 aminoácidos con una elevada homología entre los miembros de la familia. Aunque estudiados generalmente como proteínas que estimulan el crecimiento de fibroblastos, ya no es un requerimiento esta distinción para ser miembro de la familia de los factores de crecimiento de fibroblastos.
Descriptor Portuguese: Fatores de Crescimento de Fibroblastos
Descriptor French: Facteurs de croissance fibroblastique
Entry term(s): DNA Synthesis Factor
Fibroblast Growth Factor
Fibroblast Growth Regulatory Factor
Growth Factor, Fibroblast
Growth Factors, Fibroblast
Tree number(s): D12.644.276.624
D12.776.467.624
D23.529.624
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005346
Scope note: A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 62031-54-3
CAS Type 1 Name: Fibroblast growth factor
Previous Indexing: Fibroblasts (1974-1983)
Growth Substances (1974-1983)
Mitogens (1974-1983)
Nerve Tissue Proteins (1974-1983)
Peptides (1974-1983)
Pituitary Hormones (1974-1983)
Public MeSH Note: 2001; see FIBROBLAST GROWTH FACTOR 1984-2001
History Note: 2001(1984)
Related: Receptors, Fibroblast Growth Factor MeSH
DeCS ID: 5481
Unique ID: D005346
NLM Classification: QU 107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/05/31
Revision Date: 2006/07/05
Fibroblast Growth Factors - Preferred
Concept UI M0008437
Scope note A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.
Preferred term Fibroblast Growth Factors
Entry term(s) DNA Synthesis Factor
Fibroblast Growth Factor
Fibroblast Growth Regulatory Factor
Growth Factor, Fibroblast
Growth Factors, Fibroblast



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