Search
Descriptor English: Thioredoxins
Descriptor Spanish: Tiorredoxinas
Descriptor tiorredoxinas
Scope note: Proteínas donantes de hidrógeno que intervienen en diversas reacciones bioquímicas, como la reducción de ribonucleótidos y la reducción de PEROXIRREDOXINAS. La tiorredoxina se oxida a partir de un ditiol para formar un disulfuro cuando actúa como cofactor reductor. Luego el disulfuro es reducido por el NADPH en una reacción catalizada por la TIORREDOXINA REDUCTASA.
Descriptor Portuguese: Tiorredoxinas
Descriptor French: Thiorédoxines
Entry term(s): Thioredoxin
Thioredoxin 1
Thioredoxin 2
Thioredoxin-1
Thioredoxin-2
Tree number(s): D12.776.915
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013879
Scope note: Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 52500-60-4
CAS Type 1 Name: Thioredoxins
Previous Indexing: Bacterial Proteins (1968-1974)
Public MeSH Note: 2008; see THIOREDOXIN 1991, see BACTERIAL PROTEINS 1975-1990; THIOREDOXIN 2 was indexed under THIOREDOXIN & MEMBRANE PROTEINS 1997-2006
History Note: 2008(1975)
DeCS ID: 14264
Unique ID: D013879
NLM Classification: QU 55
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2007/07/09
Thioredoxins - Preferred
Concept UI M0021373
Scope note Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Preferred term Thioredoxins
Entry term(s) Thioredoxin
Thioredoxin 2 - Narrower
Concept UI M0470017
Preferred term Thioredoxin 2
Entry term(s) Thioredoxin-2
Thioredoxin 1 - Narrower
Concept UI M0505373
Preferred term Thioredoxin 1
Entry term(s) Thioredoxin-1



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey