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Descriptor English: | Prions | ||||||
Descriptor Spanish: |
Priones
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Descriptor Portuguese: | Príons | ||||||
Descriptor French: | Prions | ||||||
Entry term(s): |
Agent de l'encéphalopathie transmissible du vison |
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Tree number(s): |
D12.776.785 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D011328 | ||||||
Scope note: | Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL. |
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Allowable Qualifiers: |
AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BI biosynthèse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique DE effets des médicaments et des substances chimiques EC économie GE génétique HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PH physiologie PK pharmacocinétique PO intoxication PY pathogénicité RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UL ultrastructure UR urine |
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DeCS ID: | 19524 | ||||||
Unique ID: | D011328 | ||||||
NLM Classification: | QU 55 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1986/01/01 | ||||||
Date of Entry: | 1985/05/10 | ||||||
Revision Date: | 2020/05/27 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Acides aminés, peptides et protéines [D12]Acides aminés, peptides et protéines
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Prions
- Preferred
Agent de l'encéphalopathie transmissible du vison
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Concept UI |
M0017586 |
Preferred term | Prions |
Concept UI |
M0017585 |
Preferred term | Agent de l'encéphalopathie transmissible du vison |
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