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Descriptor English: Histocompatibility Antigens Class II
Descriptor Spanish: Antígenos de Histocompatibilidad Clase II
Descriptor antígenos de histocompatibilidad de clase II
Entry term(s) antígeno I-A
antígeno IA
antígeno de histocompatibilidad de clase II
antígeno de tipo Ia
antígeno principal de histocompatibilidad de clase II
antígenos Ia
antígenos asociados a la inmunidad
antígenos asociados a la respuesta inmunitaria
antígenos asociados a respuesta inmunitaria
antígenos de clase II
antígenos de la respuesta inmunitaria
antígenos de respuesta inmunitaria
antígenos de tipo Ia
molécula del CPH de clase II
moléculas MHC II
moléculas MHC de clase II
moléculas de clase II del MHC
moléculas de clase II del complejo principal de histocompatibilidad
moléculas del CPH de clase II
moléculas del CPH-II
moléculas del complejo principal de histocompatibilidad de clase II
proteínas de clase II del MHC
proteínas del CPH de clase II
péptido del CPH de clase II
péptidos MHC II
péptidos MHC de clase II
péptidos del CPH de clase II
péptidos del CPH-II
Scope note: Glicoproteínas (alfa y beta) transmembranales grandes, sin enlace covalentemente. Ambas cadenas pueden ser polimórficas aunque hay más variación estructural en las cadenas beta. Los antígenos de clase II en humanos se conocen como ANTÍGENOS HLA-D y se codifican por un gen en el cromosoma 6. En ratones, dos genes llamados IA e IE sobre el cromosoma 17 codifican para los antígenos H-2. Los antígenos se encuentran sobre los linfocitos B, macrófagos, células epidérmicas y espermáticas, y se piensa que median la competencia y la cooperación celular en la respuesta inmune. El término antígenos IA, usado para referirse sólo a las proteínas codificadas por los genes IA en los ratones, ahora se usa como un término genérico para cualquier antígeno de histocompatibilidad de clase II.
Descriptor Portuguese: Antígenos de Histocompatibilidade Classe II
Descriptor French: Antigènes d'histocompatibilité de classe II
Entry term(s): Antigen, Class II
Antigen, I-A
Antigen, IA
Antigens, Class II
Antigens, Ia
Antigens, Ia-Like
Antigens, Immune Response
Antigens, Immune-Associated
Antigens, Immune-Response-Associated
Class II Antigen
Class II Antigens
Class II Histocompatibility Antigen
Class II Histocompatibility Antigens
Class II MHC Proteins
Class II Major Histocompatibility Antigen
Class II Major Histocompatibility Antigens
Class II Major Histocompatibility Molecules
I A Antigen
I-A Antigen
I-A-Antigen
IA Antigen
Ia Antigens
Ia Like Antigens
Ia-Like Antigen
Ia-Like Antigens
Immune Associated Antigens
Immune Response Antigens
Immune Response Associated Antigens
Immune-Associated Antigens
Immune-Response-Associated Antigens
MHC Class II Molecule
MHC Class II Molecules
MHC II Molecules
MHC II Peptide
MHC II Peptides
MHC-II Molecules
Molecules, MHC-II
Peptides, MHC II
Tree number(s): D09.400.430.890.509
D12.776.395.550.509
D12.776.543.550.440
D23.050.301.500.400
D23.050.705.552.410
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000949
Scope note: Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
Annotation: human & animal; see also HLA ANTIGENS & specifics for human
Allowable Qualifiers: AD administration & dosage
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: HLA Antigens (1975-1980)
Histocompatibility Antigens (1973-1980)
Isoantigens (1973-1980)
Public MeSH Note: 1989; see ANTIGENS, IMMUNE RESPONSE 1981-88
History Note: 1989 (1973); use ANTIGENS, IMMUNE RESPONSE 1981-88
Related: Genes, MHC Class II MeSH
DeCS ID: 24381
Unique ID: D000949
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1981/01/01
Date of Entry: 1980/05/13
Revision Date: 2018/02/06
Histocompatibility Antigens Class II - Preferred
Concept UI M0001420
Scope note Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
Preferred term Histocompatibility Antigens Class II
Entry term(s) Antigen, Class II
Antigen, I-A
Antigen, IA
Antigens, Class II
Antigens, Ia
Antigens, Ia-Like
Antigens, Immune Response
Antigens, Immune-Response-Associated
Class II Antigen
Class II Antigens
Class II Histocompatibility Antigen
Class II Histocompatibility Antigens
Class II MHC Proteins
Class II Major Histocompatibility Antigen
Class II Major Histocompatibility Antigens
Class II Major Histocompatibility Molecules
I A Antigen
I-A Antigen
I-A-Antigen
IA Antigen
Ia Antigens
Ia Like Antigens
Ia-Like Antigen
Ia-Like Antigens
Immune Response Antigens
Immune Response Associated Antigens
Immune-Response-Associated Antigens
MHC Class II Molecule
MHC Class II Molecules
MHC II Molecules
MHC II Peptide
MHC II Peptides
MHC-II Molecules
Molecules, MHC-II
Peptides, MHC II
Immune-Associated Antigens - Broader
Concept UI M0001421
Preferred term Immune-Associated Antigens
Entry term(s) Antigens, Immune-Associated
Immune Associated Antigens



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