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Descriptor in English: Cystatins
Descriptor in Spanish: Cistatinas
Descriptor in Portuguese: Cistatinas
Descriptor in French: Cystatines
Entry term(s): Cystatin Related Proteins
Cystatin Superfamily
Cystatin-Related Proteins
Cystatins, Type 1
Cystatins, Type 2
Cystatins, Type 3
Cystatins, Type I
Cystatins, Type II
Cystatins, Type III
Stefins
Type 1 Cystatins
Type 2 Cystatins
Type 3 Cystatins
Type I Cystatins
Type II Cystatins
Type III Cystatins
Tree number(s): D12.776.215
Scope note: A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 90
DeCS UI: 24594
Descriptor UI: D015891
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2011/06/24
Cystatins - Preferred
Concept UI M0024322
Scope note A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
Preferred term Cystatins
Entry term(s) Cystatin Superfamily
Type 3 Cystatins - Narrower
Concept UI M0517013
Scope note Cystatins that occur as plasma proteins.
Preferred term Type 3 Cystatins
Entry term(s) Cystatins, Type 3
Cystatins, Type III
Type III Cystatins
Type 2 Cystatins - Narrower
Concept UI M0517012
Scope note Cystatins that occur primarily as extracellular proteins.
Preferred term Type 2 Cystatins
Entry term(s) Cystatins, Type 2
Cystatins, Type II
Type II Cystatins
Cystatin-Related Proteins - Related but not broader or narrower
Concept UI M0517011
Preferred term Cystatin-Related Proteins
Entry term(s) Cystatin Related Proteins
Type 1 Cystatins - Narrower
Concept UI M0516521
Scope note Cystatins that occur primarily as intracellular proteins.
Preferred term Type 1 Cystatins
Entry term(s) Cystatins, Type 1
Cystatins, Type I
Stefins
Type I Cystatins



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