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Descriptor English: Ankyrins
Descriptor Spanish: Ancirinas
Descriptor anquirinas
Scope note: Familia de proteínas asociadas a la membrana responsables de la adhesión del citoesqueleto. Las isoformas de la anquirina asociadas a los hematíes unen el citoesqueleto de ESPECTRINA a una proteína transmembranaria (PROTEÍNA 1 DE INTERCAMBIO DE ANIONES DEL HEMATÍE) en la membrana plasmática del hematíe. También existen isoformas de anquirina asociadas al cerebro.
Descriptor Portuguese: Anquirinas
Descriptor French: Ankyrines
Entry term(s): Ankyrin
Tree number(s): D12.776.543.080
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017487
Scope note: A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.
Annotation: membrane proteins; from the Greek word for anchor with ref to their role in attachment of the cytoskeleton; /drug eff /ultrastruct permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Blood Proteins (1979-1992)
Membrane Proteins (1979-1992)
Public MeSH Note: 93; ANKYRIN was indexed under BLOOD PROTEINS & MEMBRANE PROTEINS 1979-92
Online Note: use ANKYRINS (NM) to search ANKYRINS 1979-92
History Note: 93; was ANKYRIN (NM) 1979-92
DeCS ID: 30845
Unique ID: D017487
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/13
Revision Date: 2017/06/30
Ankyrins - Preferred
Concept UI M0026529
Scope note A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.
Preferred term Ankyrins
Entry term(s) Ankyrin



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