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Descriptor English: Bcl-2-Like Protein 11
Descriptor Spanish: Proteína 11 Similar a Bcl2
Descriptor proteína 11 similar a Bcl2
Entry term(s) mediador de muerte celular de interacción con Bcl2
mediador de muerte celular que interacciona con Bcl2
proteína BCL2L11
proteína BIM
proteína BIM de unión a Bcl-2
Scope note: Proteína similar a BCL-2 que contiene un dominio C-terminal con homología BCL-2 (BH3). Forma heterodímeros con otras PROTEÍNAS PROTO-ONCOGÉNICAS C-BCL-2. Es una inductora potente de la APOPTOSIS y la ANOICIS. Se expresan varias isoformas (BimEL, Bim L, Bim-alfa, Bim-s y Bim-gamma) que tienen distintas potencias para inducir la apoptosis.
Descriptor Portuguese: Proteína 11 Semelhante a Bcl-2
Descriptor French: Protéine-11 analogue à Bcl-2
Entry term(s): 11, Bcl-2-Like Protein
BCL2L11 Protein
BIM Bcl-2-Binding Protein
BIM Protein
Bcl 2 Binding Protein, BIM
Bcl 2 Interacting Mediator of Cell Death
Bcl 2 Like Protein 11
Bcl-2-Binding Protein, BIM
Bcl-2-Interacting Mediator of Cell Death
Protein 11, Bcl-2-Like
Protein, BCL2L11
Protein, BIM
Protein, BIM Bcl-2-Binding
Tree number(s): D12.644.360.075.323
D12.776.476.075.323
D12.776.543.116
D12.776.624.664.700.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072224
Scope note: A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; BCL-2-LIKE PROTEIN 11 was indexed under MEMBRANE PROTEINS; PROTO-ONCOGENE PROTEINS; APOPTOSIS REGULATORY PROTEINS 2005-2016; and under CARRIER PROTEINS 1998-2005
History Note: 2017 (1998)
DeCS ID: 56545
Unique ID: D000072224
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/11
Revision Date: 2016/07/11
Bcl-2-Like Protein 11 - Preferred
Concept UI M0286286
Scope note A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.
Preferred term Bcl-2-Like Protein 11
Entry term(s) 11, Bcl-2-Like Protein
BCL2L11 Protein
BIM Bcl-2-Binding Protein
BIM Protein
Bcl 2 Binding Protein, BIM
Bcl 2 Interacting Mediator of Cell Death
Bcl 2 Like Protein 11
Bcl-2-Binding Protein, BIM
Bcl-2-Interacting Mediator of Cell Death
Protein 11, Bcl-2-Like
Protein, BCL2L11
Protein, BIM
Protein, BIM Bcl-2-Binding



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