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Descriptor English: Podoplanin
Descriptor Spanish: Podoplanina
Descriptor Portuguese: Podoplanina
Descriptor French: Without translation
Tree number(s): D09.400.430.890.017
D12.776.395.550.017
D12.776.543.550.079
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000098853
Scope note: A cell-surface mucin-like glycoprotein that is encoded by the PDPN gene and is commonly found in the PULMONARY ALVEOLI, HEART, and endothelium of lymphatic vessels. It interacts with the C-type lectin-like receptor 2 (CLEC-2), expressed on BLOOD PLATELETS. It may also function in TUMOR development and progression.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Membrane Glycoproteins (1997-2024)
Public MeSH Note: 2025
History Note: 2025
DeCS ID: 60904
Unique ID: D000098853
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2025/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/08/08
Podoplanin - Preferred
Concept UI M000767423
Scope note A cell-surface mucin-like glycoprotein that is encoded by the PDPN gene and is commonly found in the PULMONARY ALVEOLI, HEART, and endothelium of lymphatic vessels. It interacts with the C-type lectin-like receptor 2 (CLEC-2), expressed on BLOOD PLATELETS. It may also function in TUMOR development and progression.
Preferred term Podoplanin



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